1-(2-(Trifluoromethyl)phenyl)-1H-imidazole , 98% , 25371-96-4

Synonym(s):
TRIM

CAS NO.：25371-96-4

Empirical Formula: C10H7F3N2

Molecular Weight: 212.17

MDL number: MFCD00041206

EINECS: 636-734-9

PRODUCT Properties

• Melting point: 43 °C
• Boiling point: 75°C 0,02mm
• Density: 1.3253 (estimate)
• Flash point: 75°C/0.025mm
• storage temp.: 2-8°C
• solubility: Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 20 mg/ml).
• form: White solid.
• pka: 4.96±0.10(Predicted)
• color: White
• biological source: synthetic (organic)
• Sensitive: Light Sensitive
• BRN: 3955637
• Stability: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
• CAS DataBase Reference: 25371-96-4(CAS DataBase Reference)

Description and Uses

TRIM (25371-96-4) is a potent inhibitor of neuronal and inducible nitric oxide synthases, (IC50?= 28.2 and 27.0 μM respectively). Inhibits endothelial NOS with lower potency (IC50 = 1057.5 μM).1?TRIM displays antinociceptive activity?in vivo.2

TRIM is a potent inhibitor of neuronal nitric oxide synthase in vitro, in animal models.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazard Note: Irritant
• HazardClass: IRRITANT, LIGHT SENSITIVE
• HS Code: 29339900