BD9078431
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-methylpent-4-enoic acid , 97% , 288617-71-0
Synonym(s):
(S)-N-Fmoc-α-2-n-propenylalanine;Fmoc-(S)-2-(2-propenyl)alanine;Fmoc-(S)-2-amino-2-methyl-4-pentenoic acid
| Pack Size | Price | Stock | Quantity |
| 100mg | RMB396.80 | In Stock |
|
| 250mg | RMB637.60 | In Stock |
|
| 1g | RMB1631.20 | In Stock |
|
| 5g | RMB6222.40 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 564.3±45.0 °C(Predicted) |
| Density | 1.224 |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| pka | 3.81±0.11(Predicted) |
| form | liquid |
| color | pale yellow |
| InChIKey | FNCSRFHDUZYOCR-NRFANRHFSA-N |
Description and Uses
Olefinic alpha-methyl amino acid for peptide stapling. Upon incorporation of this amino acid into a peptide, along with another of the same or derivative with a different length of the olefinic side chain, the two can be ′stapled′ via a ring closing metathesis reaction with Grubb′s catalyst (product # 579726). The resulting stapled peptide macrocycle has been shown to stabilize the alpha-helical structure of peptides, which can lead to favorable biological characteristics such as increased proteolytic stability and cellular uptake.
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