N-(Cyanomethyl)-4-(trifluoromethyl)nicotinamide , 95% , 158062-67-0

CAS NO.：158062-67-0

Empirical Formula: C9H6F3N3O

Molecular Weight: 229.16

MDL number: MFCD07364026

PRODUCT Properties

• Melting point: 157.5°
• Boiling point: 406.6±45.0 °C(Predicted)
• Density: 1.377±0.06 g/cm3(Predicted)
• storage temp.: -20°C Freezer
• solubility: DMSO (Slightly), Methanol (Slightly), Ethanol (Slightly, Heated)
• pka: 10.99±0.46(Predicted)
• form: Solid
• color: Light Beige to Beige
• InChI: InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16)
• InChIKey: RLQJEEJISHYWON-UHFFFAOYSA-N
• SMILES: C1=NC=CC(C(F)(F)F)=C1C(NCC#N)=O
• LogP: 0.840 (est)
• EPA Substance Registry System: Flonicamid (158062-67-0)

Description and Uses

Flonicamid is a pyridinecarboxamide insecticide. It inhibits the brown planthopper (N. lugens) inward-rectifying potassium channel K_ir1 (IC₅₀ = 0.64 μM). Flonicamid (100 μg/ml) inhibits aphid (M. persicae) salivation and sap ingestion during feeding on Japanese radish leaves. It induces toxicity in the aphid species A. gossypii, R. padi, S. graminum, and L. erysimi (LC₅₀s = 0.64, 0.74, 0.78, and 2.01 μg/ml, respectively) and rats (LD₅₀ = ≥844 mg/kg). Formulations containing flonicamid have been used for the control of pest insects in agriculture.

Flonicamid is a novel insecticide with rapid inhibitory effect against aphid feeding. Useful in cannabis testing kits as a component of pesticide mixes (P698240).

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P264-P270-P301+P312+P330-P501
• Hazard Codes: Xn
• Risk Statements: 22
• WGK Germany: 2
• HS Code: 29333990
• Hazardous Substances Data: 158062-67-0(Hazardous Substances Data)
• Toxicity: LD50 in male, female rats (mg/kg): 884, 1768 orally; in rats (mg/kg): >5000 dermally; in rats (mg/m3): >4900 by inhalation; LC50 in carp, rainbow trout (mg/l): >100, >91.9 (Morita)