rel-((1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-yl)methyl(4-nitrophenyl)carbonate , 95% , 1263166-91-1

CAS NO.：1263166-91-1

Empirical Formula: C17H17NO5

Molecular Weight: 315.33

MDL number:

PRODUCT Properties

• Boiling point: 475.7±37.0 °C(Predicted)
• Density: 1.32±0.1 g/cm3(Predicted)
• solubility: DMSO : 100 mg/mL (317.14 mM; Need ultrasonic)
• form: Solid
• color: White to off-white

Description and Uses

endo-BCN-PNP-carbonate is a very reactive compound which can easily react with amine-containing molecules in organic solvents. PNP is a good leaving group. The BCN is used for copper-free Click Chemistry reactions.

endo-BCN-O-PNB is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. endo-BCN-O-PNB is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P280-P301+P312-P302+P352-P305+P351+P338