Home Categories (1R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline
BD8775931

(1R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline , 98% , 180272-45-1

CAS NO.:180272-45-1

Empirical Formula: C15H15N

Molecular Weight: 209.29

MDL number:

Pack Size Price Stock Quantity
100mg RMB137.60 In Stock
250mg RMB204.80 In Stock
1g RMB513.60 In Stock
5g RMB1719.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 78-79℃
Density  1.065
storage temp.  2-8°C
solubility  Chloroform (Slightly), Dichloromethane (Sparingly), DMSO (Slightly), Methanol (Slightly)
form  Solid
color  White to Pale Beige

Description and Uses

(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is the counterpart to (S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline, the latter enantiomer being a key intermediate in the preparation of Solifenacin (S676700), an antimuscarinic agent. Since (R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is produced as a by-product, it has been suggested that it should be recycled in order to obtain the S enantiomer on a larger scale. (R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is also used as a reagent to prepare quinuclidin-3-yl 1,2,3,4-tetrahydroisoquinoline-2-carboxylate derivatives, compounds that act as muscarinic receptor antagonists.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

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