BD8611655
α-Angelicalactone , 98%+(sumofisomers) , 591-12-8
Synonym(s):
4-Hydroxy-3-pentenoic acid γ-lactone;5-Methyl-2(3H)-furanone;alpha-Angelica lactone
CAS NO.：591-12-8
Empirical Formula: C5H6O2
Molecular Weight: 98.1
MDL number: MFCD00005375
EINECS: 209-701-8
| Pack Size | Price | Stock | Quantity |
| 5g | RMB108.00 | In Stock |
|
| 25g | RMB304.00 | In Stock |
|
| 100g | RMB976.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 13-17 °C(lit.) |
| Boiling point: | 55-56 °C12 mm Hg(lit.) |
| Density | 1.092 g/mL at 25 °C(lit.) |
| refractive index | n |
| FEMA | 3293 | 4-HYDROXY-3-PENTENOIC ACID LACTONE |
| Flash point: | 155 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform, Ethyl Acetate |
| form | Oil |
| pka | pK1:4.3 (25°C) |
| Specific Gravity | 1.101.092 |
| color | Clear Light Yellow |
| Odor | at 10.00 % in dipropylene glycol. sweet solvent nutty tonka coumarin tobacco |
| Odor Type | coconut |
| Water Solubility | 5 g/100 mL (25 ºC) |
| Merck | 14,647 |
| JECFA Number | 221 |
| BRN | 108394 |
| LogP | 0.84 |
| CAS DataBase Reference | 591-12-8(CAS DataBase Reference) |
| NIST Chemistry Reference | 2(3H)-Furanone, 5-methyl-(591-12-8) |
| EPA Substance Registry System | 5-Methyl-2(3H)-furanone (591-12-8) |
Description and Uses
alpha-Angelicalactone acts as acancer chemopreventive agent. It is used in the synthesis of glutathione and the activity of glutathione-S-transferase and UDP-glucunonosyltransferase detoxification enzymes in esophagus, stomach, intestine, and liver. It is used in oral care formulations to round out mint notes and in coffee flavors.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H303-H227 |
| Precautionary statements | P210-P280-P403+P235-P501-P210e-P280a-P370+P378a-P501a |
| Safety Statements | 24/25 |
| RIDADR | NA 1993 / PGIII |
| WGK Germany | 2 |
| RTECS | LU5075000 |
| F | 10-21 |
| TSCA | Yes |
| HS Code | 29322090 |
| Toxicity | LD50 orl-mus: 2800 mg/kg DCTODJ 3,249,80 |
