Lipoic acid , 95% , 1200-22-2

Synonym(s):
(R)-(+)-1,2-Dithiolane-3-pentanoic acid;(R)-6,8-Dithiooctanoic acid;(R)-6,8-Thioctic acid

CAS NO.：1200-22-2

Empirical Formula: C8H14O2S2

Molecular Weight: 206.33

MDL number: MFCD01631142

EINECS: 638-752-2

PRODUCT Properties

• Melting point: 48-52 °C(lit.)
• alpha: D23 +104° (c = 0.88 in benzene)
• Boiling point: 185-195 °C(Press: 0.5 Torr)
• Density: 1.218±0.06 g/cm3(Predicted)
• refractive index: 114 ° (C=1, EtOH)
• Flash point: >230 °F
• storage temp.: -20°C
• solubility: Acetonitrile (Slightly), Chloroform (Slightly), DMSO
• form: Solid
• pka: 5.4(at 25℃)
• color: Light Yellow to Yellow
• optical activity: [α]20/D +104°, c = 1 in chloroform
• Merck: 14,9326
• LogP: 2.160 (est)

Description and Uses

α-Lipoic acid has been used as a reference standard for the analysis of α-lipoic acid in human plasma by high performance liquid chromatography coupled to electron capture detector (HPLC-ECD), in various food matrices and dietary supplements by HPLC combined with coulometric electrode array detector (CEAD) as well as electrospray ionization mass spectrometer (ESI-MS).
It may be used as a reference standard for the determination of α-lipoic acid in human urine by isocratic reversed-phase HPLC and in α-lipoic acid capsules by HPLC with chemiluminescence detection.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319
• Precautionary statements: P264-P270-P280-P301+P312+P330-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P501
• Risk Statements: 22-36/38
• Safety Statements: 20-36-26-35
• WGK Germany: 3
• HS Code: 29349990