BD8571431
(S)-Diethyl 2-(5-(methylamino)thiophene-2-carboxamido)pentanedioate , 95% , 112889-02-8
| Pack Size | Price | Stock | Quantity |
| 250mg | RMB131.20 | In Stock |
|
| 1g | RMB328.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 519.6±50.0 °C(Predicted) |
| Density | 1.231 |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 12.89±0.46(Predicted) |
Description and Uses
N-[[5-(Methylamino)-2-thienyl]carbonyl]-L-glutamic Acid Diethyl Ester can be used as reactant/reagent for synthetic preparation of Raltitrexed (anticancer agent). An intermediate or impurity in the synthesis of Raltitrexed (R100500). Raltitrexed (R100500) is folate-based inhibitor of thymidylate synthase; rapidly and extensively metabolized to its more potent polyglutamate derivatives. Antineoplastic.
