BD8570631
(2S,3R)-tert-Butyl 6-oxo-2,3-diphenylmorpholine-4-carboxylate , 95% , 112741-50-1
Synonym(s):
tert-Butyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate
CAS NO.：112741-50-1
Empirical Formula: C21H23NO4
Molecular Weight: 353.41
MDL number: MFCD00074953
EINECS: 627-150-5
| Pack Size | Price | Stock | Quantity |
| 250mg | RMB106.40 | In Stock |
|
| 1g | RMB264.00 | In Stock |
|
| 5g | RMB827.20 | In Stock |
|
| 10g | RMB1384.00 | In Stock |
|
| 25g | RMB2767.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 206 °C (dec.)(lit.) |
| Boiling point: | 509.6±50.0 °C(Predicted) |
| alpha | 86 º (c=5.5 in methylene chloride) |
| Density | 1.175±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | -3.28±0.60(Predicted) |
| optical activity | [α]20/D +86°, c = 5.5 in methylene chloride |
| InChIKey | MRUKRSQUUNYOFK-MOPGFXCFSA-N |
| CAS DataBase Reference | 112741-50-1(CAS DataBase Reference) |
Description and Uses
(2S,3R)-(+)-N-Boc-6-oxo-2,3-diphenylmorpholine (Williams chiral auxiliary) can be used as a reactant:
- In the asymmetric synthesis of cylindrospermopsin and related alkaloids via an intramolecular 1,3-dipolar cycloaddition reaction.
- To synthesize boc-3-(1-methylcyclopropyl)-D-alanine, which is used as an intermediate to prepare 4-fluoroproline-based analogs as potent tripeptide thrombin inhibitors.
- In the total synthesis of potent hepatotoxic alkaloid 7-epicylindrospermopsin by intramolecular 1,3-dipolar cycloaddition and nitroaldol reaction.
- To prepare differentially functionalized diaminoglutamic acids via radical reaction of selenide with methyl 2-acetamidoacrylate.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-37/39 |
| WGK Germany | 3 |
