Home Categories Biochemical Engineering (2R,3S,5R)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
BD8543131

(2R,3S,5R)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite , 98% , 102212-98-6

Synonym(s):
Cytidine, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-, 3′-[2-cyanoethyl bis(1-methylethyl)phosphoramidite];DMT-dC(bz) amidite;N4-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxycytidine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite];N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxycytidine, 3′-[2-cyanoethyl N,N-?bis(1-methylethyl)phosphoramidite]

CAS NO.:102212-98-6

Empirical Formula: C46H52N5O8P

Molecular Weight: 833.91

MDL number: MFCD00036315

EINECS: 801-520-8

Pack Size Price Stock Quantity
250mg RMB37.60 In Stock
1g RMB97.60 In Stock
5g RMB336.00 In Stock
25g RMB1276.00 In Stock
100g RMB4592.00 In Stock
500g RMB18368.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: >84°C (dec.)
Density  1.23 at 20℃
vapor pressure  0-0Pa at 20-50℃
storage temp.  Sealed in dry,2-8°C
solubility  Chloroform, DMSO, Methanol (Slightly)
form  powder or granules
pka 8.65±0.20(Predicted)
color  white to off-white
InChIKey PGTNFMKLGRFZDX-SALLYJDFSA-N
SMILES O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C=CC(NC(=O)C3=CC=CC=C3)=NC2=O)C[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,45,r|
LogP 6.5 at 20℃

Description and Uses

5'-O-DMT-N4-Benzoyl-2'-deoxycytidine 3'-CE phosphoramidite is used to prepare antisense oligonucleotides containing conformationally constrained methoxyaminomethylene and aminooxymethylene and aminomethylene bridged nucleoside analogs.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
Safety Statements  24/25
WGK Germany  3
HS Code  29349990

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