3-(3-Chloropropyl)-1,3-dihydro-7,8-dimethoxy-2H-3-benzazepin-2-one , 97% , 85175-59-3

CAS NO.：85175-59-3

Empirical Formula: C15H18ClNO3

Molecular Weight: 295.76

MDL number: MFCD09955404

EINECS: 617-684-7

PRODUCT Properties

• Melting point: 100-102 °C(Solv: ethanol (64-17-5))
• Boiling point: 484.1±45.0 °C(Predicted)
• Density: 1.191±0.06 g/cm3(Predicted)
• storage temp.: Sealed in dry,Store in freezer, under -20°C
• solubility: Chloroform (Slightly), Methanol (Slightly)
• form: Solid
• pka: -1.23±0.20(Predicted)
• color: White to Off-White

Description and Uses

(Z)-3-(3-chloropropyl)-7,8-diethyl-1H-benzo[d] azepin-2 (3H)-one is the side chain of ivabradine hydrochloride. Ivabradine and its medicinal salts, especially its hydrochloride, have very important pharmacological and therapeutic properties, especially, in slowing down the heart rate. Relating compounds can be used to treat or prevent various clinical myocardial ischemia conditions, such as angina pectoris, myocardial infarction and related rhythm disorders, various pathologies involving rhythm disorders, especially supraventricular rhythm disorders.

3-(3-Chloropropyl)-7,8-dimethoxy-1H-3-benzazepin-2(3H)-one is a reactant used in the synthesis of Zatebradine analogues as potential blockers od hyperpolarization-activated current.

Safety

• Signal word: Danger
• Hazard statements: H332-H312-H302
• Precautionary statements: P280-P302+P352-P312-P322-P363-P501-P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312
• HS Code: 29339900