BD8384131
Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate , 97% , 160844-75-7
CAS NO.:160844-75-7
Empirical Formula: C18H20N2O3S
Molecular Weight: 344.43
MDL number: MFCD09833701
EINECS: 927-913-5
Pack Size | Price | Stock | Quantity |
250mg | RMB53.60 | In Stock |
|
1g | RMB132.80 | In Stock |
|
5g | RMB404.80 | In Stock |
|
10g | RMB652.00 | In Stock |
|
25g | RMB1309.60 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 176 °C |
Boiling point: | 497.1±55.0 °C(Predicted) |
Density | 1.22 |
storage temp. | Sealed in dry,Room Temperature |
solubility | DMSO (Slightly, Heated), Methanol (Very Slightly, Heated) |
form | Solid |
pka | 1.02±0.10(Predicted) |
color | White to Off-White |
InChI | InChI=1S/C18H20N2O3S/c1-5-22-18(21)16-12(4)20-17(24-16)13-6-7-15(14(8-13)9-19)23-10-11(2)3/h6-8,11H,5,10H2,1-4H3 |
InChIKey | OGAZOYHQFBSRMC-UHFFFAOYSA-N |
SMILES | S1C(C(OCC)=O)=C(C)N=C1C1=CC=C(OCC(C)C)C(C#N)=C1 |
CAS DataBase Reference | 160844-75-7(CAS DataBase Reference) |
Description and Uses
Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate is an impurity of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H315-H319 |
Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 |
HS Code | 2934.10.2000 |