(S)-2-(Butylsulfonamido)-3-(4-(4-(piperidin-4-yl)butoxy)phenyl)propanoicacidhydrochloride , 97% , 142373-60-2
CAS NO.:142373-60-2
Empirical Formula: C22H39ClN2O6S
Molecular Weight: 495.07
MDL number: MFCD00868210
Pack Size | Price | Stock | Quantity |
1g | RMB1663.20 | In Stock |
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others | Enquire |
PRODUCT Properties
Melting point: | 83-87oC |
solubility | Methanol (Slightly) |
form | Solid |
color | White |
CAS DataBase Reference | 142373-60-2 |
Description and Uses
Tirofiban was launched as Aggrastat in Switzerland and the US for patients with unstable angina or non-Q-wave myocardial infarction to prevent cardiac ischemic events. Tirofiban is synthesized from (S)-tyrosine by a fourstep process. Tirofiban is a novel highly potent antiplatelet agent that inhibits the interaction of fibrinogen with GPⅡb/Ⅲa, an activated platelet membrane-bound glycoprotein complex. It prevents arterial thrombus formation in a dosedependent manner. Clinical efficacy was highly significant with an absolute and relative risk reduction. In these studies, treatment with tirofiban was well tolerated, without significant adverse effects.
Tirofiban Hydrochloride is a selective nonpeptide platelet glycoprotein IIb/IIIa antagonist.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |