Home Categories Pharmaceutical intermediates (S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol
BD8307331

(S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol , 95% , 877397-65-4

CAS NO.:877397-65-4

Empirical Formula: C8H7Cl2FO

Molecular Weight: 209.04

MDL number: MFCD09863793

EINECS: 700-699-9

Pack Size Price Stock Quantity
250mg RMB20.00 In Stock
1g RMB24.00 In Stock
5g RMB57.60 In Stock
10g RMB91.20 In Stock
25g RMB222.40 In Stock
100g RMB860.80 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 261.3±35.0 °C(Predicted)
Density  1.406±0.06 g/cm3(Predicted)
storage temp.  2-8°C
pka 13.30±0.20(Predicted)
form  Solid
color  White
InChI InChI=1/C8H7Cl2FO/c1-4(12)7-5(9)2-3-6(11)8(7)10/h2-4,12H,1H3/t4-/s3
InChIKey JAOYKRSASYNDGH-UFLUHPNLNA-N
SMILES [C@H](C1C(=CC=C(F)C=1Cl)Cl)(O)C |&1:0,r|
CAS DataBase Reference 877397-65-4

Description and Uses

(S) -1- (2,6-dichloro-3-fluorophenyl) ethanol(C8H7C12FO) is synthesized (R)-3-[l-(2, 6-dichloro-3-fluoro-benzene)- The key intermediate of ethoxy-5- (l-piperidine-4-hydroxy-1 hydrogen-pyrazole-4-hydroxy) -pyrimidine-2-indane. And (R)-3-[l-(2,6-dichloro-3-fluoro-benzene)-ethoxy-5-(l-piperidine-4-hydroxy-1 hydrogen-pyrazole-4-hydroxy) -Pyrimidine-2-indane is a small molecule kinase inhibitor for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) positive for anaplastic lymphohematokinase (ALK).

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H317-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
HazardClass  IRRITANT
HS Code  2906290090

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