Dicyclohexylamine (S)-2-(((benzyloxy)carbonyl)amino)-3,3-dimethylbutanoate , 98% , 62965-37-1

Synonym(s):
Z-L-tert-Leucine (dicyclohexylammonium) salt

CAS NO.：62965-37-1

Empirical Formula: C14H19NO4.C12H23N

Molecular Weight: 446.63

MDL number: MFCD02262225

PRODUCT Properties

• Melting point: 163-167 °C
• Density: 1.1 at 20℃
• vapor pressure: 0Pa at 25℃
• storage temp.: 2-8°C
• form: Solid
• PH: 6.3 (H2O, 20℃)(saturated solution)
• optical activity: [α]20/D 6.5±1°, c = 1% in methanol
• BRN: 3831936
• LogP: 1.6 at 25℃ and pH2.5
• Surface tension: 63mN/m at 1g/L and 20℃

Description and Uses

3-methyl-N-[(phenylmethoxy)carbonyl]-L-Valine, with N-cyclohexylcyclohexanamine is used in the preparation of an intermediate towards the interleukin-1β converting enzyme inhibitor VX-765 using the palladium-catalyzed coupling of a bromodihydrofuranone with Cbz-L-prolinamide as the key step.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• Safety Statements: 22-24/25
• WGK Germany: 3
• F: 10-21
• HS Code: 2906190090