Tribenoside , 97% , 10310-32-4

Synonym(s):
Ethyl 3,5,6-tri-O-benzyl-D-glucofuranoside

CAS NO.：10310-32-4

Empirical Formula: C29H34O6

Molecular Weight: 478.58

MDL number: MFCD00801089

EINECS: 233-687-2

PRODUCT Properties

• alpha: D26 +8° (chloroform)
• Boiling point: bp1.2 270-280°
• Density: 1.19±0.1 g/cm3(Predicted)
• storage temp.: Sealed in dry,Store in freezer, under -20°C
• solubility: Practically insoluble in water, very soluble in acetone, in methanol and in methylene chloride.
• pka: 13.01±0.70(Predicted)
• color: Pale Yellow to Light Yellow
• InChIKey: ULLNJSBQMBKOJH-VIVFLBMVSA-N
• SMILES: O(CC)C1O[C@H]([C@@H](COCC2=CC=CC=C2)OCC2=CC=CC=C2)[C@H](OCC2=CC=CC=C2)[C@H]1O
• CAS DataBase Reference: 10310-32-4

Description and Uses

Tribenoside is the semisynthetic sugar derivate ethyl-3, 5, 6-tri-O-benzyl-D-glucofuranoside, glucose with one ethyl and three benzyl groups. It is widely used in capsule (cps) form for oral administration and cream or suppositories for topical application under several brand names. Tribenoside is indicated for the treatment of chronic venous insufficiency, hemorrhoids, and arthritis. It has a high affinity for the vessel wall and a wide spectrum of pharmacological effects, including venotonic, anti-edematous, fibrinolysis-promoting, analgesic, anti-inflammatory (inhibiting histamine and prostaglandins), anti-allergic, membrane-stabilizing, and bactericidal effects. It regulates the expression and localization of laminins in epidermal cells to reconstruct basement membranes in wound healing[1].

Sclerosing agent.

Safety

• Hazard statements: H411
• Toxicity: LD50 oral in rat: > 20gm/kg