BD8168231
tert-Butyl 4-bromo-2-fluorobenzoate , 98% , 889858-12-2
CAS NO.：889858-12-2
Empirical Formula: C11H12BrFO2
Molecular Weight: 275.11
MDL number: MFCD08703426
| Pack Size | Price | Stock | Quantity |
| 1g | RMB88.80 | In Stock |
|
| 5g | RMB283.20 | In Stock |
|
| 10g | RMB456.80 | In Stock |
|
| 25g | RMB836.80 | In Stock |
|
| 100g | RMB2345.60 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 305.7±27.0 °C(Predicted) |
| Density | 1.394±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Oil |
| color | Clear Colourless |
Description and Uses
tert-Butyl 4-Bromo-2-fluorobenzoate is an intermediate of enzalutamide (M199800). Enzalutamide is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. MDV 3100 has also been shown to induce tumor cell apoptosis, and has no agonist activity. MDV 3100 is a candidate for the treatment of castration-resistant prostate cancer.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H227-H302-H315-H319-H335-H412 |
| Precautionary statements | P210-P261-P305+P351+P338 |
| HS Code | 2916399090 |
