2-Nitro-1-naphthol , 98% , 607-24-9
CAS NO.:607-24-9
Empirical Formula: C10H7NO3
Molecular Weight: 189.17
MDL number: MFCD00003956
EINECS: 210-131-7
Pack Size | Price | Stock | Quantity |
1g | RMB33.60 | In Stock |
|
5g | RMB120.80 | In Stock |
|
10g | RMB195.20 | In Stock |
|
25g | RMB434.40 | In Stock |
|
100g | RMB1530.40 | In Stock |
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others | Enquire |
PRODUCT Properties
Melting point: | 123-125 °C (lit.) |
Boiling point: | 324.41°C (rough estimate) |
Density | 1.3175 (rough estimate) |
refractive index | 1.5400 (estimate) |
storage temp. | Sealed in dry,Room Temperature |
pka | 6.13±0.50(Predicted) |
form | Powder |
InChI | InChI=1S/C10H7NO3/c12-10-8-4-2-1-3-7(8)5-6-9(10)11(13)14/h1-6,12H |
InChIKey | MUCCHGOWMZTLHK-UHFFFAOYSA-N |
SMILES | C1(O)=C2C(C=CC=C2)=CC=C1[N+]([O-])=O |
CAS DataBase Reference | 607-24-9(CAS DataBase Reference) |
NIST Chemistry Reference | 2-Nitro-1-naphthol(607-24-9) |
Description and Uses
2-Nitro-1-naphthol is an important organic compound with anti-inflammatory properties used as an analytical method for measuring albumin concentration and as an enzyme-labelled substrate in electrochemical immunoassays. The substance reacts with albumin to form a coloured complex which can be detected spectrophotometrically. It is also used as a model system for the study of inflammatory diseases and inhibits p38 kinase activity. In addition, a derivative of 2-Nitro-1-naphthol (4-nitro-1-naphthol) can be used to prepare chromogenic substrates for neutral or slightly acidic hydrolases.
2-Nitro-1-naphthol was employed as substrate for use in an amperometric 3-electrode system for the determination of alkaline phosphatase, the enzyme label most commonly used in electrochemical immunoassays. It was also used in the preparation of:
- di-(2-nitro-1-naphthyl) hydrogen phosphate
- 1-(2′-methyl-3′-indenyl)-2-naphthylamine and -2-naphthol (axially chiral ligands)
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26-37/39-24/25-36 |
WGK Germany | 3 |
Hazard Note | Irritant |
HS Code | 29089990 |