4-(4-Aminophenyl)butanoic acid , 95% , 15118-60-2

CAS NO.：15118-60-2

Empirical Formula: C10H13NO2

Molecular Weight: 179.22

MDL number: MFCD00075052

EINECS: 628-142-4

PRODUCT Properties

• Melting point: 121-124 °C (lit.) 121-133 °C
• Boiling point: 363.7±17.0 °C(Predicted)
• Density: 1.177±0.06 g/cm3(Predicted)
• storage temp.: Keep in dark place,Inert atmosphere,Room temperature
• solubility: DMSO (Slightly), Methanol (Slightly)
• form: Solid
• pka: 4.70±0.10(Predicted)
• color: Light Beige to Light Brown
• InChI: InChI=1S/C10H13NO2/c11-9-6-4-8(5-7-9)2-1-3-10(12)13/h4-7H,1-3,11H2,(H,12,13)
• InChIKey: RBHLFWNKEWLHBP-UHFFFAOYSA-N
• SMILES: C1(CCCC(O)=O)=CC=C(N)C=C1
• CAS DataBase Reference: 15118-60-2(CAS DataBase Reference)

Description and Uses

4-(4-Aminophenyl)butyric acid (4-APB) is an important organic compound derived from butyric acid, which is used as a synthetic intermediate for pharmaceuticals or the synthesis of various compounds. It is also used in drug mechanism studies and is thought to be an agonist for certain G-protein coupled receptors and may also interact with other proteins in the signal transduction pathway. In addition, 4-(4-aminophenyl)butyric acid has been found to inhibit monoamine oxidase, which plays a role in neurotransmitter catabolism.

4-(4-Aminophenyl)butyric Acid is a degradation product of Chlorambucil (C325050); an alkylating agent that is used as an chemotherapy drug in the treatment of chronic lymphocytic leukemia. Chlorambucil is also used to treat non-Hodgkin''s lymphoma (NHL) and Hodgkin''s disease.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• HS Code: 2922498590