Mal-PEG2-NHSEster , 98+% , 1433997-01-3
CAS NO.:1433997-01-3
Empirical Formula: C15H18N2O8
Molecular Weight: 354.31
MDL number: MFCD24539465
Pack Size | Price | Stock | Quantity |
100mg | RMB572.80 | In Stock |
|
250mg | RMB970.40 | In Stock |
|
1g | RMB2627.20 | In Stock |
|
others | Enquire |
PRODUCT Properties
Boiling point: | 524.3±60.0 °C(Predicted) |
Density | 1.42±0.1 g/cm3(Predicted) |
solubility | Soluble in DCM |
pka | -2.34±0.20(Predicted) |
form | Oil |
color | Colourless |
Description and Uses
Mal-PEG2-NHS ester is a PEG linker containing a maleimide group and an NHS ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
Mal-?PEG2-?NHS Ester is a reagent used in the preparation of antibody-drug conjugates that bind to human-antigen targets in the effort to combat cancers.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H335-H319-H315 |
Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 |