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BD7539248

Mal-PEG2-NHSEster , 98+% , 1433997-01-3

CAS NO.:1433997-01-3

Empirical Formula: C15H18N2O8

Molecular Weight: 354.31

MDL number: MFCD24539465

Pack Size Price Stock Quantity
100mg RMB572.80 In Stock
250mg RMB970.40 In Stock
1g RMB2627.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 524.3±60.0 °C(Predicted)
Density  1.42±0.1 g/cm3(Predicted)
solubility  Soluble in DCM
pka -2.34±0.20(Predicted)
form  Oil
color  Colourless

Description and Uses

Mal-PEG2-NHS ester is a PEG linker containing a maleimide group and an NHS ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Mal-?PEG2-?NHS Ester is a reagent used in the preparation of antibody-drug conjugates that bind to human-antigen targets in the effort to combat cancers.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H335-H319-H315
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362

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