![N-(3-(7-((1,3-Dimethyl-1H-pyrazol-5-yl)amino)-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide](https://img.chemicalbook.com/CAS/GIF/839707-37-8.gif)
BD5528653
N-(3-(7-((1,3-Dimethyl-1H-pyrazol-5-yl)amino)-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide , 98+% , 839707-37-8
Synonym(s):
N-[3-[7-(2,5-Dimethyl-2H-pyrazol-3-ylamino)-1-methyl-2-oxo-1,4-dihydro-2H-pyrimido[4,5-d]pyrimidin-3-yl]-4-methylphenyl]-3-trifluoromethyl-benzamide;Pluripotin;SC 1;SC-1
CAS NO.：839707-37-8
Empirical Formula: C27H25F3N8O2
Molecular Weight: 550.53
MDL number: MFCD20527253
EINECS: 804-647-7
| Pack Size | Price | Stock | Quantity |
| 1mg | RMB452.00 | In Stock |
|
| 5mg | RMB791.20 | In Stock |
|
| 10mg | RMB1385.60 | In Stock |
|
| 25mg | RMB2591.20 | In Stock |
|
| 50mg | RMB3886.40 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Density | 1.43 |
| storage temp. | -20°C |
| solubility | DMSO: soluble10mg/mL (clear solution) |
| pka | 12.82±0.70(Predicted) |
| form | powder |
| color | white to beige |
| InChIKey | NBZFRTJWEIHFPF-UHFFFAOYSA-N |
Description and Uses
Pluripotin is a dual inhibitor of ERK1 and RasGAP with KDs of 98 nM and 212 nM, respectively. Pluripotin also inhibits RSK1, RSK2, RSK3, and RSK4 with IC50s of 0.5, 2.5, 3.3, and 10.0 μM, respectively.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P280-P302+P352 |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 45 |
| WGK Germany | 3 |
| HS Code | 2933399990 |