BD5024741
Erythromycylamine , 95% , 26116-56-3
CAS NO.:26116-56-3
Empirical Formula: C37H70N2O12
Molecular Weight: 734.96
MDL number:
EINECS: 406-790-7
Pack Size | Price | Stock | Quantity |
100mg | RMB296.80 | In Stock |
|
250mg | RMB447.20 | In Stock |
|
1g | RMB1124.80 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 123-127°C |
Boiling point: | 810.3±65.0 °C(Predicted) |
Density | 1.19±0.1 g/cm3(Predicted) |
storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
solubility | DMF: 15 mg/ml; DMSO: 15 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml |
form | A solid |
pka | 13.41±0.70(Predicted) |
color | White to off-white |
Description and Uses
(9S)-9-Amino-9-deoxoerythromycin is a semi-synthetic analogue of erythromycin prepared by reduction of erythromycin oxime. (9S)-9-Amino-9-deoxoerythromycin is a potent antibiotic, however the introduction of the amino- moiety increases the compound’s polarity and is disadvantageous for in vivo use. This limitation was overcome by the synthesis of dirithromycin, a Schiff base pro-drug that dissociates in vivo to erythromycylamine.
Safety
Symbol(GHS) | GHS05,GHS09 |
Signal word | Danger |
Hazard statements | H318-H410 |
Precautionary statements | P280-P305+P351+P338-P310-P273-P391-P501 |
Hazard Codes | Xi,N |
Risk Statements | 41-50/53 |
Safety Statements | 26-39-60-61 |
Toxicity | mouse,LD50,intraperitoneal,120mg/kg (120mg/kg),European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 13, Pg. 83, 1978. |