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BD5024741

Erythromycylamine , 95% , 26116-56-3

CAS NO.:26116-56-3

Empirical Formula: C37H70N2O12

Molecular Weight: 734.96

MDL number:

EINECS: 406-790-7

Pack Size Price Stock Quantity
100mg RMB296.80 In Stock
250mg RMB447.20 In Stock
1g RMB1124.80 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 123-127°C
Boiling point: 810.3±65.0 °C(Predicted)
Density  1.19±0.1 g/cm3(Predicted)
storage temp.  Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility  DMF: 15 mg/ml; DMSO: 15 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml
form  A solid
pka 13.41±0.70(Predicted)
color  White to off-white

Description and Uses

(9S)-9-Amino-9-deoxoerythromycin is a semi-synthetic analogue of erythromycin prepared by reduction of erythromycin oxime. (9S)-9-Amino-9-deoxoerythromycin is a potent antibiotic, however the introduction of the amino- moiety increases the compound’s polarity and is disadvantageous for in vivo use. This limitation was overcome by the synthesis of dirithromycin, a Schiff base pro-drug that dissociates in vivo to erythromycylamine.

Safety

Symbol(GHS) 
GHS05,GHS09
Signal word  Danger
Hazard statements  H318-H410
Precautionary statements  P280-P305+P351+P338-P310-P273-P391-P501
Hazard Codes  Xi,N
Risk Statements  41-50/53
Safety Statements  26-39-60-61
Toxicity mouse,LD50,intraperitoneal,120mg/kg (120mg/kg),European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 13, Pg. 83, 1978.

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