SGC0946 , 98% , 1561178-17-3

Synonym(s):
1-(3-((((2R,3S,4R,5R)-5-(4-Amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(isopropyl)amino)propyl)-3-(4-(tert-butyl)phenyl)urea;5-Bromo-7-[5-deoxy-5-[[3-[[[[4-(1,1-dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-beta-D-7H-Pyrrolo[2,3-d]pyrimidin-4-amine

CAS NO.：1561178-17-3

Empirical Formula: C28H40BrN7O4

Molecular Weight: 618.57

MDL number: MFCD26523136

EINECS: 808-588-8

PRODUCT Properties

• Melting point: 125-126o C
• Boiling point: 771.5±60.0 °C(Predicted)
• Density: 1.48±0.1 g/cm3(Predicted)
• storage temp.: -20°C
• solubility: DMSO: soluble20mg/mL, clear
• pka: 12.39±0.70(Predicted)
• form: powder
• color: white to beige

Description and Uses

SGC0946 is a potent DOT1L methyltransferase inhbiitor used in the treatment of leukemia seen effectively in vitro.

Safety

• Symbol(GHS): GHS06
• Signal word: Danger
• Hazard statements: H301
• Precautionary statements: P301+P310
• Hazard Codes: T
• Risk Statements: 25
• Safety Statements: 45
• RIDADR: UN 2811 6.1 / PGIII
• WGK Germany: 3
• HS Code: 2934999090