4-(4-(tert-Butyl)-2-ethoxyphenyl)-2-(2,6-difluorophenyl)-4,5-dihydrooxazole , 96% , 153233-91-1

Synonym(s):
(RS)-5-tert-Butyl-2-[2-(2,6-difluorophenyl)-4,5-dihydro-1,3-oxazol-4-yl]phenetole;4-(4-tert-Butyl-2-ethoxyphenyl)-2-(2,6-difluorophenyl)-4,5-dihydrooxazole

CAS NO.：153233-91-1

Empirical Formula: C21H23F2NO2

Molecular Weight: 359.41

MDL number: MFCD07363987

EINECS: 201-167-4

PRODUCT Properties

• Melting point: 101-102°
• Boiling point: 449.1±45.0 °C(Predicted)
• Density: 1.15±0.1 g/cm3(Predicted)
• Flash point: 457℃
• storage temp.: Sealed in dry,2-8°C
• solubility: Chloroform (Slightly), Methanol (Slightly)
• pka: 2.04±0.70(Predicted)
• form: Solid
• color: White to Off-White
• BRN: 8930214
• Stability: Hygroscopic
• InChI: InChI=1S/C21H23F2NO2/c1-5-25-18-11-13(21(2,3)4)9-10-14(18)17-12-26-20(24-17)19-15(22)7-6-8-16(19)23/h6-11,17H,5,12H2,1-4H3
• InChIKey: IXSZQYVWNJNRAL-UHFFFAOYSA-N
• SMILES: O1CC(C2=CC=C(C(C)(C)C)C=C2OCC)N=C1C1=C(F)C=CC=C1F

Description and Uses

Etoxazole is an organofluorine acaricide. It induces toxicity in two-spotted spider mite (T. urticae) larvae (LC₅₀ = 0.036 mg/L for the London reference strain) through inhibition of chitin synthase 1. It reduces acetylcholinesterase (AChE) activity in the freshwater fish O. niloticus in a concentration-dependent manner. Etoxazole (2.2-22 mg/kg per day) inhibits the activity of catalase, glutathione peroxidase (GPX), and AChE in the liver and kidneys of rats in a dose-dependent manner. Formulations containing etoxazole have been used for the control of mites in agriculture.

Acaricide.

Safety

• Symbol(GHS): GHS09
• Signal word: Warning
• Hazard statements: H410
• Precautionary statements: P273
• Hazard Codes: N
• Risk Statements: 50/53
• Safety Statements: 60-61
• RIDADR: UN 3077 9 / PGIII
• WGK Germany: 3
• RTECS: RP6795100
• Toxicity: LD50 in rats (mg/kg): >5000 orally; >2000 dermally; LC50 (96 hr) in Japanese carp: 0.89 mg/l (Ishida)