BD4555241
3,6-Dichlorobenzo[b]thiophene-2-carboxylicacid , 97% , 34576-94-8
Pack Size | Price | Stock | Quantity |
100mg | RMB38.40 | In Stock |
|
250mg | RMB90.40 | In Stock |
|
1g | RMB242.40 | In Stock |
|
5g | RMB734.40 | In Stock |
|
10g | RMB1257.60 | In Stock |
|
25g | RMB2514.40 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Boiling point: | 426.4±40.0 °C(Predicted) |
Density | 1.653±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | Soluble in DMSO (up to at least 20 mg/ml) |
form | solid |
pka | 2.09±0.30(Predicted) |
color | Off-white |
Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
Description and Uses
3,6-dichloro-benzo[b]thiophene-2-Carboxylic acid is an inhibitor of myeloid cell leukemia 1 (Mcl-1) with a Ki value of 59 μM for binding of FITC-Mcl-1-BH2 peptide binding to Mcl-1. It has been used as a building block in the synthesis of inhibitors of Mcl-1, the toll-like receptor 3/double-stranded RNA (TLR3/dsRNA) complex, and D-amino acid oxidase (DAO).
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H315-H319-H302-H335 |
Precautionary statements | P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |