Home Categories (3R,4S)-tert-Butyl3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate
BD3560648

(3R,4S)-tert-Butyl3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate , 98+% , 201856-57-7

CAS NO.:201856-57-7

Empirical Formula: C18H25NO5

Molecular Weight: 335.39

MDL number:

EINECS: 1592732-453-0

Pack Size Price Stock Quantity
1g RMB4123.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 459.6±45.0 °C(Predicted)
Density  1.16
storage temp.  2-8°C
pka -4.97±0.60(Predicted)
CAS DataBase Reference 201856-57-7(CAS DataBase Reference)

Description and Uses

(3R,4S)-3-(1-Ethoxyethoxy)-2-oxo-4-phenyl-1-azetidinecarboxylic acid 1,1-Dimethylethyl ester is used as a reagent in the synthesis of abeo-taxane derivatives that possess broad inhibitory effects against proliferation of colon cancer, melanoma, and renal cancer cell lines. (3R,4S)-3-(1-Ethoxyethoxy)-2-oxo-4-phenyl-1-azetidinecarboxylic acid 1,1-Dimethylethyl ester is also used as a reagent in the synthesis of a novel D-ring modified Docetaxel (D494420) analogue which has proven to have equipotent cytotoxicity in relation to Paclitaxel (P132500) towards cancer cell lines.

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