BD3560648
(3R,4S)-tert-Butyl3-(1-ethoxyethoxy)-2-oxo-4-phenylazetidine-1-carboxylate , 98+% , 201856-57-7
CAS NO.:201856-57-7
Empirical Formula: C18H25NO5
Molecular Weight: 335.39
MDL number:
EINECS: 1592732-453-0
Pack Size | Price | Stock | Quantity |
1g | RMB4123.20 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Boiling point: | 459.6±45.0 °C(Predicted) |
Density | 1.16 |
storage temp. | 2-8°C |
pka | -4.97±0.60(Predicted) |
Description and Uses
(3R,4S)-3-(1-Ethoxyethoxy)-2-oxo-4-phenyl-1-azetidinecarboxylic acid 1,1-Dimethylethyl ester is used as a reagent in the synthesis of abeo-taxane derivatives that possess broad inhibitory effects against proliferation of colon cancer, melanoma, and renal cancer cell lines. (3R,4S)-3-(1-Ethoxyethoxy)-2-oxo-4-phenyl-1-azetidinecarboxylic acid 1,1-Dimethylethyl ester is also used as a reagent in the synthesis of a novel D-ring modified Docetaxel (D494420) analogue which has proven to have equipotent cytotoxicity in relation to Paclitaxel (P132500) towards cancer cell lines.