Home Categories Pharmaceutical intermediates 4-(Pyridin-3-yl)pyrimidin-2-amine
BD3481745

4-(Pyridin-3-yl)pyrimidin-2-amine , 97% , 66521-66-2

CAS NO.:66521-66-2

Empirical Formula: C9H8N4

Molecular Weight: 172.19

MDL number: MFCD01317832

EINECS: 1312995-182-4

Pack Size Price Stock Quantity
250mg RMB28.00 In Stock
1g RMB57.60 In Stock
5g RMB232.00 In Stock
10g RMB448.00 In Stock
25g RMB945.60 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 189-191 °C
Boiling point: 439.9±37.0 °C(Predicted)
Density  1.259±0.06 g/cm3(Predicted)
storage temp.  under inert gas (nitrogen or Argon) at 2–8 °C
solubility  DMSO (Slightly), Methanol (Slightly)
form  Solid
pka 2.76±0.10(Predicted)
color  Off-White to Pale Yellow
InChI InChI=1S/C9H8N4/c10-9-12-5-3-8(13-9)7-2-1-4-11-6-7/h1-6H,(H2,10,12,13)
InChIKey LQHQKYWYKPLKCH-UHFFFAOYSA-N
SMILES C1(N)=NC=CC(C2=CC=CN=C2)=N1

Description and Uses

4-(3-Pyridinyl)-2-pyrimidinamine serves as an intermediate compound during the synthesis of Nilotinib. Nilotinib is a selective tyrosine kinase receptor inhibitor used in the therapy of chronic myelogenous leukemia.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Hazard Codes  T
Risk Statements  25-20/21/22
Safety Statements  45-36/37
HS Code  29339900

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