(2S)-1-[(1S)-1-[Bis(1,1-dimethylethyl)phosphino]ethyl]-2-(diphenylphosphino)ferrocene , 98%99%ee , 277306-29-3

Synonym(s):
(2S)-1-[(1S)-1-[Bis(1,1-dimethylethyl)phosphino]ethyl]-2-(diphenylphosphino)ferrocene (acc to CAS);Josiphos SL-J002-2

CAS NO.：277306-29-3

Empirical Formula: C32H34FeP2

Molecular Weight: 536.42

MDL number: MFCD01074443

PRODUCT Properties

• alpha: +412° ±15° (c 0.5, CHCl3)
• storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
• form: Powder
• color: orange
• optical activity: [α]20/D +410±15°, c = 0.5 in chloroform

Description and Uses

(S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldi-tert-butylphosphine is β-boration catalyst; used in preparation of Sitagliptin β-Amino-2,4,5-trifluorobenzenebutanoic Acid derivatives intermediates via Grignard exchange reaction, cross coupling, β-boration, oxidation and Amination.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P280-P301+P312-P302+P352-P305+P351+P338
• Safety Statements: 22-24/25
• WGK Germany: 3
• F: 10
• HS Code: 29319090