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BD3120748

Isoacteoside , 98% , 61303-13-7

Synonym(s):
(E)-2-(3,4-dihydroxyphenyl)ethyl 3-O-(6-deoxy-α-L-mannopyranosyl)-, 6-(3-(3,4-dihydroxyphenyl)-β-D-glucopyranoside;Isoacteoside;Isoverbascoside

CAS NO.:61303-13-7

Empirical Formula: C29H36O15

Molecular Weight: 624.59

MDL number: MFCD06798947

Pack Size Price Stock Quantity
50mg RMB779.20 In Stock
100mg RMB1245.60 In Stock
250mg RMB2116.80 In Stock
1g RMB5714.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 220~230℃
Boiling point: 942.9±65.0 °C(Predicted)
Density  1.60±0.1 g/cm3(Predicted)
storage temp.  under inert gas (nitrogen or Argon) at 2-8°C
solubility  DMSO : ≥ 48 mg/mL (76.85 mM)
form  Powder
pka 9.32±0.10(Predicted)
color  White to yellow

Description and Uses

Isoverbascoside is a phenylethanoid glycoside that has been found in C. trichotomum and has diverse biological activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals in a cell-free assay and inhibits hydrogen peroxide-induced lipid peroxidation in V79-4 cells when used at a concentration of 10 μg/ml. Isoverbascoside (7.5-30 μM) induces apoptosis and production of reactive oxygen species (ROS) in, and reduces viability of, OVCAR-3 cells. It inhibits tumor growth in an OVCAR-3 mouse xenograft model when administered at a dose of 30 mg/kg. Isoverbascoside (2.5 and 5 mg/kg) decreases brain amyloid deposition and increases exploratory behavior in rats when infused into the cerebral ventricles with amyloid-β (1-42) (Aβ42; ). It also decreases xylene-induced ear edema in mice and increases survival in a mouse model of LPS-induced endotoxic shock.

Isoacteoside is a possible food antioxidant.

Safety

HS Code  29389090

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