Home Categories (S)-2-Amino-5-((4-nitrophenyl)amino)-5-oxopentanoicacidhydrochloride
BD2816149

(S)-2-Amino-5-((4-nitrophenyl)amino)-5-oxopentanoicacidhydrochloride , 97% , 67953-08-6

Synonym(s):
L-γ-Glutamyl-p-nitroanilide

CAS NO.:67953-08-6

Empirical Formula: C11H14ClN3O5

Molecular Weight: 303.7

MDL number: MFCD00039054

EINECS: 267-944-5

Pack Size Price Stock Quantity
10mg RMB304.80 In Stock
25mg RMB716.80 In Stock
50mg RMB1219.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

storage temp.  2-8°C
solubility  Soluble in Water (up to 5 mg/ml).
form  solid
color  Off-white
Stability: Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 1 month.
EPA Substance Registry System L-Glutamine, N-(4-nitrophenyl)-, monohydrochloride (67953-08-6)

Description and Uses

L-γ-Glutamyl-p-nitroanilide (67953-08-6; GPNA) is a substrate for γ-glutamyl transpeptidase. GPNA is used for the determination of γ-glutamyl transpeptidase hydrolytic activity via spectrophotometric monitoring of p-nitroaniline released by the action of the enzyme on GPNA.1 GPNA has also been shown to be an inhibitor of glutamine uptake – solute-linked carrier family A1 member 5 (SLC1A5).2?Cellular uptake of L-glutamine (regulated by SLC1A5) is a rate-limiting step that activates mTOR and is, thus, an interesting cancer chemotherapy target.3

L-Glutamic acid gamma-(p-nitroanilide) is used in methods of treating cancers having a deregulated NRF2/KEAP1 pathway.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Safety Statements  22-24/25
WGK Germany  3

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