5-Methylbenzo[d][1,3]dioxole , 95% , 7145-99-5

Synonym(s):
5-Methyl-1,3-benzodioxole

CAS NO.：7145-99-5

Empirical Formula: C8H8O2

Molecular Weight: 136.15

MDL number: MFCD00005833

EINECS: 230-453-1

PRODUCT Properties

• Boiling point: 199-200 °C (lit.)
• Density: 1.135 g/mL at 25 °C (lit.)
• refractive index: n20/D 1.532(lit.)
• Flash point: 169 °F
• storage temp.: 2-8°C

Description and Uses

3,4-(Methylenedioxy)toluene can be used as a cation scavenger for the selective cleavage of 4-(3,4-dimethoxyphenyl)benzyl (DMPBn) ethers affording the corresponding deprotected products in the presence of trifluoroacetic acid (TFA) in anhydrous CH₂Cl₂.
It can also be used as a starting material to prepare:

• 1,3-Benzodioxole-5-carboxaldehyde via photooxidation using CBr₄.
• 6-Methyl-1,3-benzodioxole-5-carboxaldehyde by treating with dichloromethylmethyl ether and TiCl₄.

Safety

• Symbol(GHS): GHS05,GHS07
• Signal word: Danger
• Hazard statements: H302-H318
• Precautionary statements: P264-P270-P280-P301+P312-P305+P351+P338-P501
• Hazard Codes: Xn
• Risk Statements: 22-41
• Safety Statements: 26-39
• WGK Germany: 3
• RTECS: DF4921090