Home Categories 3,4-Di(1H-indol-3-yl)-1-methyl-1H-pyrrole-2,5-dione
BD1396448

3,4-Di(1H-indol-3-yl)-1-methyl-1H-pyrrole-2,5-dione , 98% , 113963-68-1

Synonym(s):
2,3- bis(1H-Indol-3-yl)-N-methylmaleimide, Ro 31-6045;2,3-bis(1H-Indol-3-yl)-N-methylmaleimide, Ro 31-6045;Bisindolylmaleimide V - CAS 113963-68-1 - Calbiochem

CAS NO.:113963-68-1

Empirical Formula: C21H15N3O2

Molecular Weight: 341.36

MDL number: MFCD00236433

EINECS: 604-604-1

Pack Size Price Stock Quantity
1g RMB2455.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: >260 °C
Boiling point: 655.7±55.0 °C(Predicted)
Density  1.450±0.06 g/cm3(Predicted)
storage temp.  Sealed in dry,Store in freezer, under -20°C
solubility  DMSO: soluble
form  solid
pka 15.89±0.30(Predicted)
color  Orange
Stability: Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
CAS DataBase Reference 113963-68-1(CAS DataBase Reference)

Description and Uses

Ro 31-6045 (113963-68-1) is a bis indolylmaleimide derivative that is a potent inhibitor of the mitogen-stimulated protein kinase p70 (S6K) acting independently of its upstream activator mTOR.1?Does not inhibit PKC (at concentrations <100?mM) and therefore may be used as a negative control for bisindolylmaleimide PKC inhibitors2?such as GF 109203X3?and other structurally related inhibitors4.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
WGK Germany  3

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