BD1318148
((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronicacid , 98+% , 1132709-15-9
CAS NO.:1132709-15-9
Empirical Formula: C19H25BN4O4
Molecular Weight: 384.24
MDL number: MFCD26940312
Pack Size | Price | Stock | Quantity |
1g | RMB5818.40 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Density | 1.214±0.06 g/cm3(Predicted) |
storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
solubility | Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly) |
form | Solid |
pka | 9.66±0.43(Predicted) |
color | White to Off-White |
Description and Uses
(1R,2R)-Bortezomib is a diastereomer of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |