Home Categories ((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronicacid
BD1318148

((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronicacid , 98+% , 1132709-15-9

CAS NO.:1132709-15-9

Empirical Formula: C19H25BN4O4

Molecular Weight: 384.24

MDL number: MFCD26940312

Pack Size Price Stock Quantity
1g RMB5818.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Density  1.214±0.06 g/cm3(Predicted)
storage temp.  under inert gas (nitrogen or Argon) at 2-8°C
solubility  Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly)
form  Solid
pka 9.66±0.43(Predicted)
color  White to Off-White

Description and Uses

(1R,2R)-Bortezomib is a diastereomer of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

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