(R,E)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoic acid , 97% , 1012341-48-8

CAS NO.：1012341-48-8

Empirical Formula: C23H27NO4

Molecular Weight: 381.46

MDL number:

PRODUCT Properties

• Melting point: 188 - 191°C
• Boiling point: 595.6±50.0 °C(Predicted)
• Density: 1.132±0.06 g/cm3(Predicted)
• vapor pressure: 8.4-839.931Pa at 20℃
• storage temp.: Sealed in dry,Room Temperature
• solubility: DMSO (Slightly), Methanol (Slightly)
• pka: 4.67±0.19(Predicted)
• form: Solid
• color: White to Off-White
• InChI: InChI=1S/C23H27NO4/c1-16(21(25)26)14-20(24-22(27)28-23(2,3)4)15-17-10-12-19(13-11-17)18-8-6-5-7-9-18/h5-14,20H,15H2,1-4H3,(H,24,27)(H,25,26)/b16-14+/t20-/m0/s1
• InChIKey: JXTNUXJSXXIIFE-VISDOYDDSA-N
• SMILES: C(O)(=O)/C(/C)=C/[C@H](NC(OC(C)(C)C)=O)CC1=CC=C(C2=CC=CC=C2)C=C1
• LogP: 2.2-3.6 at 25℃ and pH2.5-7

Description and Uses

(R,E)-5-([1,1-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-methylpent-2-enoic Acid is used in preparation of sacubitril intermediate using Nickel Salt catalyst.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P305+P351+P338