BD0905348
1-(9,10-Dihydro-6H-6,10-methanoazepino[4,5-g]quinoxalin-8(7H)-yl)-2,2,2-trifluoroethanone , 98+% , 230615-70-0
CAS NO.:230615-70-0
Empirical Formula: C15H12F3N3O
Molecular Weight: 307.27
MDL number: MFCD23701601
Pack Size | Price | Stock | Quantity |
1g | RMB3698.40 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 164-166 ºC |
Boiling point: | 491.9±45.0 °C(Predicted) |
Density | 1.449 |
storage temp. | 2-8°C |
solubility | Chloroform (Slightly), Methanol (Slightly) |
pka | 1.50±0.20(Predicted) |
form | Solid |
color | White to Off-White |
Description and Uses
7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (N-(trifluoroacetyl)varenicline) is an important pharmaceutical intermediate compound which is used in the preparation of varenicline. Varenicline is an oral smoking cessation aid drug. It works by blocking the pleasant effects of nicotine (from smoking) on the brain.
7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine is used to prepare varenicline, which is a smoking cessation. It is a Varenicline protected impurity.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |