Home Categories Pharmaceutical intermediates Ethyl6-oxo-1,6-dihydropyrimidine-5-carboxylate
BD0857745

Ethyl6-oxo-1,6-dihydropyrimidine-5-carboxylate , 98% , 4786-52-1

CAS NO.:4786-52-1

Empirical Formula: C7H8N2O3

Molecular Weight: 168.15

MDL number: MFCD00235034

Pack Size Price Stock Quantity
1g RMB83.20 In Stock
5g RMB245.60 In Stock
25g RMB995.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 185-186 °C
Density  1.33±0.1 g/cm3(Predicted)
storage temp.  Inert atmosphere,Room Temperature
pka 7.70±0.40(Predicted)

Description and Uses

7-Chloroisoquinolin-1(2H)-one acts as a reagent for the preparation, SAR of methoxyisoquinoline derivative and discovery of asunaprevir (BMS-650032), an orally efficacious NS3 protease inhibitor for the treatment of hepatitis C virus infection. Synthesis and pharmacological evaluation of a series of 1,2-dihydro-1-[(5-methyl-1-imidazol-4-yl)methyl]-2-oxopyridine 5-HT3 antagonists.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H335-H302-H315-H319
Precautionary statements  P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
HazardClass  IRRITANT
HS Code  2933599590

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