(4S,4aS,5aS,6S,12aS)-4-(Dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide , 85%+(HPLC) , 60-54-8

CAS NO.：60-54-8

Empirical Formula: C22H24N2O8

Molecular Weight: 444.43

MDL number: MFCD00150881

EINECS: 200-481-9

PRODUCT Properties

• Melting point: 175-177 °C(lit.)
• alpha: D25 -257.9° (0.1N HCl); D25 -239° (methanol)
• Boiling point: 554.44°C (rough estimate)
• Density: 1.3809 (rough estimate)
• refractive index: 1.6500 (estimate)
• storage temp.: 2-8°C
• solubility: 95% ethanol: soluble12.5mg/mL
• form: powder
• pka: pKa (50% aq DMF): 8.3, 10.2(at 25℃)
• color: yellow to yellow orange
• optical activity: [α]25/D -239° in methanol (Specific rotation ) &_& [α]25/D -257.9°, c = 0.1 M HCl mol (Specific rotation )
• Water Solubility: Limited solubility in water. Soluble in 1M HCl with heating.
• Merck: 13,9271
• BRN: 2230417
• BCS Class: 3
• Stability: Hygroscopic
• InChIKey: OFVLGDICTFRJMM-WESIUVDSSA-N

Description and Uses

Tetracycline is an antibiotic that has been utilized in disease management situations in which SmR strains of E. amylovora or P. syringae already exist. However, tetracycline does not appear to be as effective as streptomycin in reducing blossom populations of E. amylovora (17). Additionally, strains of P. syringae with resistance to tetracycline have been isolated from pear orchards in Oregon and Washington (18), suggesting that resistance to this antibiotic will probably develop in orchards where it is applied.

antibactierial

Safety

• Symbol(GHS): GHS07,GHS08,GHS09
• Signal word: Warning
• Hazard statements: H302-H361fd-H411
• Precautionary statements: P202-P264-P270-P273-P301+P312-P308+P313
• Hazard Codes: Xn,Xi
• Risk Statements: 22-36/37/38
• Safety Statements: 22-36-26
• WGK Germany: 3
• RTECS: QI8750000
• F: 3-8-10
• HS Code: 29413000
• Toxicity: LD50 in rats, mice (mg/kg): 807, 808 orally (Goldenthal)