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BD0616245

Tylosin , 98% , 1401-69-0

Synonym(s):
Tylosin A

CAS NO.:1401-69-0

Empirical Formula: C46H77NO17

Molecular Weight: 916.1

MDL number: MFCD09881413

EINECS: 215-754-8

Pack Size Price Stock Quantity
100mg RMB56.00 In Stock
250mg RMB84.00 In Stock
1g RMB208.00 In Stock
5g RMB635.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 135-137°C
alpha  D25 -46° (c = 2 in methanol)
Boiling point: 796.05°C (rough estimate)
Density  1.1424 (rough estimate)
refractive index  1.5280 (estimate)
storage temp.  Sealed in dry,2-8°C
solubility  DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 30 mg/ml
form  A crystalline solid
pka pKa 7.73(H2O t = 25 I = 0.167) (Uncertain)
color  White to light yellow
Water Solubility  H2O: soluble 50 mg/mL
Stability: Solutions are stable at pH 4-9 (most stable at pH 7);
Below pH 4 tylosin B (desmycosin) is formed as a result of acid hydrolysis;
In neutral and alkaline pH – tylosin aldol (TAD) is formed together with polar degradation products of unknown identity;
When tylosin solution is exposed to daylight, a photodegradation product - isotylosin A (isoTA) is formed.
InChIKey WBPYTXDJUQJLPQ-VMXQISHHSA-N
EPA Substance Registry System Tylosin (1401-69-0)

Description and Uses

Occupational exposure concerns farmers, breeders, animal-feed workers and veterinarians.

Macrolide antibiotic isolated from a strain of Streptomycetes fradiae found in soil from Thailand. Antibacterial.

Safety

Symbol(GHS) 
GHS08
Signal word  Danger
Hazard statements  H317-H334
Precautionary statements  P261-P272-P280-P284-P302+P352-P333+P313
Hazard Codes  Xn,N
Risk Statements  42/43-50
Safety Statements  36-61-45-36/37-22
HS Code  2941906000
Hazardous Substances Data 1401-69-0(Hazardous Substances Data)
Toxicity Tylosin base and its salts were shown to be of low acute oral toxicity with LD50 values in excess 5000 mg/kg bw in the rat and mouse and greater than 800 mg/kg bw in the dog.

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