(R)-3-Hydroxydihydrofuran-2(3H)-one , 98% , 56881-90-4

Synonym(s):
(R)-4,5-Dihydro-3-hydroxy-2(3H)-furanone

CAS NO.：56881-90-4

Empirical Formula: C4H6O3

Molecular Weight: 102.09

MDL number: MFCD00211246

PRODUCT Properties

• alpha: +66°(23℃, c=1.15, CHCl3)
• Boiling point: 133 °C/10 mmHg (lit.)
• Density: 1.309 g/mL at 25 °C (lit.)
• refractive index: n20/D 1.467(lit.)
• Flash point: >230 °F
• storage temp.: 2-8°C
• pka: 13.07±0.20(Predicted)
• form: clear liquid
• color: Colorless to Light yellow
• Specific Gravity: 1.32
• optical activity: [α]23/D +66°, c = 1.15 in chloroform
• BRN: 80588

Description and Uses

(R)-(+)-α-Hydroxy-γ-butyrolactone can be used as a starting material to synthesize:

• δ-Azaproline by reacting with benzyloxycarbonyl aminophthalimide via Mitsunobu reactions.
• Homochiral (R)-2,4-dihydroxybutyramide seco-pseudonucleoside reagents.
• Botryolide B via esterification and ring-closing metathesis reaction.
• Pregnane derivatives containing γ-butyrolactones as potential glucocorticoid agonists.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P280-P261
• WGK Germany: 3
• HS Code: 2932209090