3-(2-Bromoethoxy)propanoicacid , 97% , 1393330-33-0
| Pack Size | Price | Stock | Quantity |
| 100mg | RMB338.40 | In Stock |
|
| 250mg | RMB506.40 | In Stock |
|
| 1g | RMB1274.40 | In Stock |
|
| 5g | RMB4460.80 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| storage temp. | -20°C |
| solubility | DMSO : 100 mg/mL (507.54 mM; Need ultrasonic) |
| form | Liquid |
| color | Colorless to light yellow |
Description and Uses
Bromo-PEG1-acid is a PEG linker containing a bromide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Bromo-PEG1-acid is a heterobifunctional, PEGylated crosslinker featuring a bromo group at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. Bromo-PEG1-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2918999090 |
