3-(2-(2-Bromoethoxy)ethoxy)propanoicacid , 97% , 1807503-92-9
| Pack Size | Price | Stock | Quantity |
| 100mg | RMB140.00 | In Stock |
|
| 250mg | RMB238.40 | In Stock |
|
| 1g | RMB642.40 | In Stock |
|
| 5g | RMB2248.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Boiling point: | 347.2±27.0 °C(Predicted) |
| Density | 1.464±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| pka | 4.27±0.10(Predicted) |
| form | Liquid |
| color | Light brown to yellow |
Description and Uses
Bromo-PEG2-acid is a PEG linker containing a bromide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Bromo-PEG2-acid is a heterobifunctional, PEGylated crosslinker featuring a bromo group at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. Bromo-PEG2-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2918999090 |
