Home Categories N1,N3-Bis(2,3-dihydroxypropyl)-5-nitroisophthalamide
BD0031148

N1,N3-Bis(2,3-dihydroxypropyl)-5-nitroisophthalamide , 95% , 76820-34-3

Synonym(s):
N,N′-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide;N,N′-Bis(2,3-dihydroxypropyl)-5-nitroisophthalamide

CAS NO.:76820-34-3

Empirical Formula: C14H19N3O8

Molecular Weight: 357.32

MDL number: MFCD08063356

Pack Size Price Stock Quantity
100mg RMB419.20 In Stock
250mg RMB712.00 In Stock
1g RMB1920.80 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: >140°C (dec.)
Density  1.347 at 20℃
storage temp.  2-8°C
solubility  DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
form  Solid
color  White to Off-White
Stability: Hygroscopic
LogP -1.36 at 23℃ and pH6

Description and Uses

N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide is a non-ionic organic compound that can be used as a reaction intermediate for the preparation of amidated iodinated x-ray contrast media. The amidation reaction is typically carried out in aqueous solution with an acid catalyst at room temperature for up to 24 hours. The amidation reaction condition and time can be optimized depending on the desired end product. Industrial preparation of iohexol typically involves the use of an x-ray generator and iopamidol, which is synthesized from diethylene triamine and ethylenediamine.

N,N'-Bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide is used in the preparation of X-ray contrast agents.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
HS Code  2924296000

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