Thionicotinamide adenine dinucleotide , ≥92% , 4090-29-3

Synonym(s):
Thionicotinamide-DPN

CAS NO.：4090-29-3

Empirical Formula: C21H27N7O13P2S

Molecular Weight: 679.49

MDL number: MFCD00079609

EINECS: 223-828-6

PRODUCT Properties

• storage temp.: -20°C
• form: powder to crystal
• color: Light orange to Yellow to Green
• InChIKey: DQRRIGAXTAXHLR-NNYOXOHSSA-N
• SMILES: O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP([O-])(=O)OC[C@@H]2[C@H]([C@@H](O)[C@H]([N+]3=CC=CC(C(=S)N)=C3)O2)O)O[C@H]1N1C=NC2C(=NC=NC1=2)N)O |&1:1,2,3,15,16,17,19,32,r|

Description and Uses

Thionicotinamide adenine dinucleotide is an analog of NAD. Use of Thio-NAD instead of NAD as a substrate for NAD(+)-consuming enzymes is more advantageous since the reduced form of Thio-NAD exhibits a substantial increase in absorbance at 405 nM, the most commonly available wavelength on microplate readers.

Thionicotinamide adenine dinucleotide has been used as a substrate analog in S-adenosyl-l-homocysteine (AdoHcy) hydrolases (SAHH) inhibition assay and in NAD+ glycohydrolase activity.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302+H312+H332-H315-H319-H335
• Precautionary statements: P280-P271
• Hazard Codes: Xn
• Risk Statements: 20/21/22-36/37/38
• Safety Statements: 26-36
• WGK Germany: -
• HS Code: 29349990