D-Luciferin potassium salt , ≥98.0%(HPLC) , 115144-35-9

Synonym(s):
(S)-2-(6-Hydroxy-2-benzothiazolyl)-2-thiazoline-4-carboxylic acid potassium salt;4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic acid potassium salt;Firefly luciferin potassium salt

CAS NO.：115144-35-9

Empirical Formula: C11H7KN2O3S2

Molecular Weight: 318.41

MDL number: MFCD00044928

EINECS: 1592732-453-0

PRODUCT Properties

• storage temp.: Inert atmosphere,Store in freezer, under -20°C
• solubility: DMF:16.7(Max Conc. mg/mL);52.45(Max Conc. mM); DMSO:7.5(Max Conc. mg/mL);23.55(Max Conc. mM); Ethanol:0.25(Max Conc. mg/mL);0.79(Max Conc. mM); PBS (pH 7.2):10.0(Max Conc. mg/mL);0.31(Max Conc. mM); Water:32.0(Max Conc. mg/mL);100.5(Max Conc. mM)
• form: A crystalline solid
• color: Light yellow
• BRN: 5416262
• InChI: InChI=1/C11H8N2O3S2.K.H/c14-5-1-2-6-8(3-5)18-10(12-6)9-13-7(4-17-9)11(15)16;;/h1-3,7,14H,4H2,(H,15,16);;/t7-;;/s3
• InChIKey: UMBKGTQQGYPQBE-OGFXRTJISA-M
• SMILES: C([C@H]1CSC(C2=NC3C=CC(O)=CC=3S2)=N1)(=O)O.[KH] |&1:1,r|

Description and Uses

D-Luciferin potassium salt(115144-35-9) is a water soluble form of D-Luciferin. D-Luciferin is a common bioluminescent substrate used for imaging of firefly luciferase expression with peak chemiluminescent emission at 560 nm. The ATP dependant luciferin oxidation is catalyzed by the Luciferase enzyme encoded by lucgene.

D-Luciferin Potassium Salt is a class of light-emitting heterocyclic compounds found in organisms that cause bioluminescence, such as firefly. This compound creates light through the process of oxidative decarboxylation by luciferase while ATP is present. In cell culture, D-Luciferin Potassium Salt is used to achieve highly sensitive bioluminescence detection. Recently, Luciferin was used to measure the uptake of mRNA in preparation of the vaccine against COVID-19.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P271-P280
• WGK Germany: 3
• HS Code: 29342000