trans-Zeatin , >98.0%(HPLC) , 1637-39-4
Synonym(s):
6-(4-Hydroxy-3-methylbut-2-enylamino)purine;N6-(4-Hydroxy-3-methyl-2-buten-1-yl)adenine
CAS NO.：1637-39-4
Empirical Formula: C10H13N5O
Molecular Weight: 219.24
MDL number: MFCD00213654
EINECS: 605-343-5
| Pack Size | Price | Stock | Quantity |
| 100MG | RMB240.80 | In Stock |
|
| 500MG | RMB692.80 | In Stock |
|
| 1G | RMB1269.60 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 207 °C |
| Boiling point: | 395.0±52.0 °C(Predicted) |
| Density | 1.40±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | H2O: soluble |
| form | powder |
| pka | 14.77±0.10(Predicted) |
| color | off-white to yellow |
| Merck | 14,10117 |
| BRN | 616241 |
| InChI | InChI=1S/C10H13N5O/c1-7(4-16)2-3-11-9-8-10(13-5-12-8)15-6-14-9/h2,5-6,16H,3-4H2,1H3,(H2,11,12,13,14,15)/b7-2+ |
| InChIKey | UZKQTCBAMSWPJD-FARCUNLSSA-N |
| SMILES | C(O)/C(/C)=C/CNC1=C2C(=NC=N1)NC=N2 |
Description and Uses
trans-Zeatin is a cytokinin plant growth regulator with antioxidant and neuroprotective activities. It binds to the cytokinin receptor Arabidopsis histidine kinase 3 (AHK3) with a KD value of 1.3 nM. trans-Zeatin increases chlorophyll levels in etiolated Cucumus sativus cotyledons in a concentration-dependent manner. It increases callus growth and shoot formation in N. tabacum calluses when used at concentrations of 5 and 50 μM. trans-Zeatin (25-100 μM) reduces production of reactive oxygen species (ROS) induced by amyloid β (25-35) (Aβ25-35) in PC12 cells. It reduces scopolamine-induced spontaneous alternations in the Y-maze, indicating enhanced spatial memory, in mice when administered at doses of 1.5, 3, and 4.5 mg/kg per day.
Zeatin, purified from Zea mays, is a member of the cytokinin group of plant growth factors, the activity of which is attributed to its more stable trans form. Trans-Zeatin inhibits UVB-induced matrix metalloproteinase-1 expression via MAP kinase signaling in human skin fibroblasts. Trans-Zeatin is a potential agent for the management of skin photoaging.
