L-Valine , 99% , 72-18-4

Synonym(s):
Val;(S)-(+)-Valine;L-2-Amino-3-methylbutanoic acid;L-Valine;(S)-α-Aminoisovaleric acid

CAS NO.：72-18-4

Empirical Formula: C5H11NO2

Molecular Weight: 117.15

MDL number: MFCD00064220

EINECS: 200-773-6

PRODUCT Properties

• Melting point: 295-300 °C (subl.) (lit.)
• alpha: 28 º (c=8, 6N HCl)
• Boiling point: 213.6±23.0 °C(Predicted)
• Density: 1.23
• refractive index: 28 ° (C=8, HCl)
• storage temp.: 2-8°C
• solubility: H₂O: 25 mg/mL
• form: powder
• pka: 2.29(at 25℃)
• color: White
• PH: 5.5-6.5 (100g/l, H2O, 20℃)
• Odor: odorless
• Odor Type: odorless
• optical activity: [α]20/D +27.0±0.5°, c = 5% in 5 M HCl
• Water Solubility: 85 g/L (20 ºC)
• λmax: λ: 260 nm Amax: 0.15; λ: 280 nm Amax: 0.1
• Merck: 14,9909
• BRN: 1721136
• InChIKey: KZSNJWFQEVHDMF-BYPYZUCNSA-N
• LogP: 0.29

Description and Uses

Valine (abbreviated as Val or V) is an α-amino acid with the chemical formula HO₂CCH(NH₂)CH(CH₃)₂. L-Valine is one of 20 proteinogenic amino acids. Its codons are GUU, GUC, GUA, and GUG. This essential amino acid is classified as nonpolar. Human dietary sources are any proteinaceous foods such as meats, dairy products, soy products, beans and legumes.
Along with leucine and isoleucine, valine is a branched-chain amino acid. It is named after the plant valerian. In sickle-cell disease, valine substitutes for the hydrophilic amino acid glutamic acid in hemoglobin. Because valine is hydrophobic, the hemoglobin is prone to abnormal aggregation.

valine is an amino acid used as a skin-conditioning and odor-masking agent. It is more commonly used in hair care preparations than in skin care.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• Hazard Codes: Xn
• Risk Statements: 40
• Safety Statements: 24/25-36-22
• WGK Germany: 3
• RTECS: YV9361000
• TSCA: Yes
• HS Code: 29224995
• Toxicity: LD50 intraperitoneal in rat: 5390mg/kg