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A8347812

Valinomycin , ≥98%(TLC),≥95%(HPLC) , 2001-95-8

Synonym(s):
Cyclo(L-Val-D-HyIva-D-Val-L-Lac-)3: HyIva = α-Hydroxyisovaleric acid, Lac = Lactic acid;Valinomycin;Valinomycin, Streptomyces fulvissimus - CAS 2001-95-8 - Calbiochem

CAS NO.:2001-95-8

Empirical Formula: C54H90N6O18

Molecular Weight: 1111.32

MDL number: MFCD00005114

EINECS: 217-896-6

Pack Size Price Stock Quantity
5mg RMB159.20 In Stock
10MG RMB263.20 In Stock
50MG RMB1039.20 In Stock
100mg RMB1599.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 187-190 °C
alpha  D20 +31.0° (c = 1.6 in benzene)
Boiling point: 821.74°C (rough estimate)
Density  1.060
refractive index  1.6400 (estimate)
Flash point: 87℃
storage temp.  2-8°C
solubility  DMSO: ≥10 mg/mL
form  solid
pka 11.32±0.70(Predicted)
color  white
optical activity [α]20/D +32±2°, c = 1.6% in benzene
Water Solubility  Soluble in DMSO at 10mg/ml. Insoluble in water
Merck  13,9976
BRN  78657
Stability: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.

Description and Uses

Valinomycin (2001-95-8) is a selective K+ ionophore capable of transporting potassium ions through lipid membranes.1 Valinomycin can induce apoptosis in cells by causing a rapid loss of mitochondrial membrane potential via potassium efflux.2,3

antibiotic; LD50 (rat, po) 4 mg/kg

Safety

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H300+H310
Precautionary statements  P262-P280-P301+P310+P330-P302+P352+P310
Hazard Codes  Xn,T,T+,Xi
Risk Statements  27/28-36/37/38-21/22
Safety Statements  36-45-36/37-28-37/39-26
RIDADR  UN 2811 6.1/PG 1
WGK Germany  3
RTECS  YV9468000
10-18-21
TSCA  Yes
HazardClass  6.1(a)
PackingGroup  I
HS Code  29419090

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