Tazobactam acid , 97% , 89786-04-9

Synonym(s):
(2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo-[3.2.0]heptanes-2-carboxylicacid-4,4-dioxide;[2S-(2α,3β,5α)]-3-Methyl-7-oxo-3-(1H,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptan-2-carbons?ure-4,4-dioxid;Tazobactam

CAS NO.：89786-04-9

Empirical Formula: C10H12N4O5S

Molecular Weight: 300.29

MDL number: MFCD00867002

EINECS: 618-303-7

PRODUCT Properties

• Melting point: 115-145℃
• Boiling point: 77℃
• Density: 1.92±0.1 g/cm3(Predicted)
• RTECS: XI0191400
• Flash point: >110°(230°F)
• storage temp.: Sealed in dry,Store in freezer, under -20°C
• solubility: DMSO (Slightly, Heated), Methanol (Slightly, Heated, Sonicated)
• pka: 2.33±0.40(Predicted)
• form: Solid
• color: White to Off-White
• Water Solubility: Soluble in water
• Stability: Light Sensitive
• InChI: InChI=1S/C10H12N4O5S/c1-10(5-13-3-2-11-12-13)8(9(16)17)14-6(15)4-7(14)20(10,18)19/h2-3,7-8H,4-5H2,1H3,(H,16,17)/t7-,8+,10+/m1/s1
• InChIKey: LPQZKKCYTLCDGQ-WEDXCCLWSA-N
• SMILES: N12[C@@]([H])(CC1=O)S(=O)(=O)[C@@](C)(CN1C=CN=N1)[C@@H]2C(O)=O

Description and Uses

Tazobactam often is coadministered with piperacillin because of tazobactam's ability to inhibit β-lactamases. T azobactam, like other β-lactamase inhibitors, has little or no antibacterial activity. This effect is analogous to that of clavulanic acid and sulbactam.

Tazobactam is a β-Lactamase inhibitor, used with β-lactam antibiotics to enhance their effect.

Safety

• Symbol(GHS): GHS07
• Signal word: Danger
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P280a-P304+P340-P305+P351+P338-P405-P501a
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HS Code: 2941106000