1-(<i>tert</i>-Butoxycarbonyl)-1,2,3,6-tetrahydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine , >98.0% , 286961-14-6

Synonym(s):
(N-tert-Butoxycarbonyl)-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester;(N-tert-Butoxycarbonyl-1,2,3,6-tetrahydropyridin-4-yl)boronic acid pinacol ester;(N-tert-Butoxycarbonyl-1,2,5,6-tetrahydropyridin-4-yl)boronic acid pinacol ester;(1-tert-Butoxycarbonyl-1,2,3,6-tetrahydropyridin-4-yl)boronic acid pinacol ester

CAS NO.：286961-14-6

Empirical Formula: C16H28BNO4

Molecular Weight: 309.21

MDL number: MFCD03840345

EINECS: 689-148-0

PRODUCT Properties

• Melting point: 114.0 to 118.0 °C
• Boiling point: 348.0±52.0 °C(Predicted)
• Density: 1.05±0.1 g/cm3(Predicted)
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• solubility: Chloroform (Sparingly), Dichloromethane (Sparingly), DMSO (Slightly)
• form: Solid
• pka: -1.21±0.40(Predicted)
• color: white to off-white
• Water Solubility: Soluble in most organic solvents. Insoluble in water.
• InChI: InChI=1S/C16H28BNO4/c1-14(2,3)20-13(19)18-10-8-12(9-11-18)17-21-15(4,5)16(6,7)22-17/h8H,9-11H2,1-7H3
• InChIKey: VVDCRJGWILREQH-UHFFFAOYSA-N
• SMILES: C1N(C(OC(C)(C)C)=O)CC=C(B2OC(C)(C)C(C)(C)O2)C1

Description and Uses

Reagent used for suzuki-Miyaura cross-coupling using palladium phosphine catalyst, palladium-catalyzed ligand-controlled regioselective Suzuki coupling, wrenchnolol derivative optimized for gene activation in cells. Also used in Preparation of several enzymatic inhibitors and receptor ligands, orally active anaplastic lymphoma kinase inhibitors and oxazolecarboxamides as diacylglycerol acyltransferase-1 inhibitors for treatment of obesity and diabetes.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P280-P305+P351+P338-P304+P340-P405-P501A
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-37-60
• WGK Germany: 3
• TSCA: No
• HazardClass: IRRITANT
• HS Code: 29349990