Tianeptine Sodium Salt Hydrate , >98.0%(HPLC) , 30123-17-2

Synonym(s):
7-[(3-Chloro-6,11-dihydro-6-methyl-dibenzo[c,f][1,2]thiazepine-11-yl)amino]heptanoic acid S,S dioxide sodium salt hydrate

CAS NO.：30123-17-2

Empirical Formula: C21H24ClN2NaO4S

Molecular Weight: 458.93

MDL number: MFCD00879851

EINECS: 250-059-3

PRODUCT Properties

• Melting point: 1800C
• storage temp.: Desiccate at RT
• solubility: DMSO: ≥20mg/mL
• form: solid
• color: white to tan
• Merck: 14,9420
• Stability: Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 2 months.
• InChIKey: ZLBSUOGMZDXYKE-UHFFFAOYSA-M
• SMILES: C1(NCCCCCCC([O-])=O)C2C=CC=CC=2N(C)S(=O)(=O)C2C=C(Cl)C=CC1=2.[Na+]

Description and Uses

Tianeptine sodium salt is a structurally novel, serotonin specific antidepressant. It is useful in the treatment of neurotic and reactive depressions, as well as depressive states accompanied by anxiety. Tianeptine (sodium salt) is an analytical reference standard categorized as an opioid. Tianeptine has been abused and associated with overdose and death. Formulations containing tianeptine have been used in the treatment of depression. This product is intended for use in analytical forensic applications. This product is also available as a general research tool .

Tianeptine sodium salt is a tricyclic compound with psychostimulant, anti-ulcer and anti-emetic properties. Tianeptine sodium salt hydrate has been used as a selective serotonin reuptake enhancer (SSRE) positive control during serotonin transporter (SERT) assay in human embryonic kidney 293 cell lines. Tianeptine (INN) (Stablon, Coaxil, Tatinol) is a SSRE drug used for treating major depressive episodes (mild, moderate, or severe). Tianeptine commonly used for depression. It is also used for pain, asthma, anxiety, and many other conditions, but there is no good scientific evidence to support these other uses.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H312-H332
• Precautionary statements: P261-P271-P304+P340-P312-P280-P302+P352-P312-P322-P363-P501-P264-P270-P301+P312-P330-P501
• WGK Germany: 3
• HS Code: 2934.99.4400